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Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous and biologically poorly understood disease. To tailor CRC treatment, it is essential to first model this heterogeneity by defining subtypes of patients with homogeneous biological and clinical characteristics and second match these subtypes to c...

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Detalles Bibliográficos
Autores principales: Schlicker, Andreas, Beran, Garry, Chresta, Christine M, McWalter, Gael, Pritchard, Alison, Weston, Susie, Runswick, Sarah, Davenport, Sara, Heathcote, Kerry, Castro, Denis Alferez, Orphanides, George, French, Tim, Wessels, Lodewyk FA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543849/
https://www.ncbi.nlm.nih.gov/pubmed/23272949
http://dx.doi.org/10.1186/1755-8794-5-66