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Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines
BACKGROUND: Colorectal cancer (CRC) is a heterogeneous and biologically poorly understood disease. To tailor CRC treatment, it is essential to first model this heterogeneity by defining subtypes of patients with homogeneous biological and clinical characteristics and second match these subtypes to c...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543849/ https://www.ncbi.nlm.nih.gov/pubmed/23272949 http://dx.doi.org/10.1186/1755-8794-5-66 |