The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency

Objective: Disulfiram is a one of the few pharmacotherapies for cocaine addiction that shows promise. Since disulfiram and cocaine both affect levels of global methylation we hypothesized the MTHFR gene, whose product is involved in supplying methyl groups for DNA and protein methylation, may be ass...

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Detalles Bibliográficos
Autores principales: Spellicy, Catherine J., Kosten, Thomas R., Hamon, Sara C., Harding, Mark J., Nielsen, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544007/
https://www.ncbi.nlm.nih.gov/pubmed/23335901
http://dx.doi.org/10.3389/fpsyt.2012.00109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544007/
https://www.ncbi.nlm.nih.gov/pubmed/23335901
http://dx.doi.org/10.3389/fpsyt.2012.00109

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