Radiosynthesis and Evaluation of [(11)C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography

[Image: see text] Fatty acid amide hydrolase (FAAH) plays a key role in regulating the tone of the endocannabinoid system. Radiotracers are required to image and quantify FAAH activity in vivo. We have synthesized a series of potent FAAH inhibitors encompassing two classes of N-alkyl-O-arylcarbamate...

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Detalles Bibliográficos
Autores principales: Wilson, Alan A., Hicks, Justin W., Sadovski, Oleg, Parkes, Jun, Tong, Junchao, Houle, Sylvain, Fowler, Christopher J., Vasdev, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544278/
https://www.ncbi.nlm.nih.gov/pubmed/23214511
http://dx.doi.org/10.1021/jm301492y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544278/
https://www.ncbi.nlm.nih.gov/pubmed/23214511
http://dx.doi.org/10.1021/jm301492y

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