Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers

DNA methylation, consisting of the addition of a methyl group at the fifth-position of cytosine in a CpG dinucleotide, is one of the most well-studied epigenetic mechanisms in mammals with important functions in normal and disease biology. Disease-specific aberrant DNA methylation is a well-recogniz...

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Detalles Bibliográficos
Autores principales: Olkhov-Mitsel, Ekaterina, Bapat, Bharati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Cancer Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544446/
https://www.ncbi.nlm.nih.gov/pubmed/23342273
http://dx.doi.org/10.1002/cam4.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544446/
https://www.ncbi.nlm.nih.gov/pubmed/23342273
http://dx.doi.org/10.1002/cam4.22

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