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The Frequency of Granulocytes with Spontaneous Somatic Mutations: A Wide Distribution in a Normal Human Population

Germ-line mutation rate has been regarded classically as a fundamental biological parameter, as it affects the prevalence of genetic disorders and the rate of evolution. Somatic mutation rate is also an important biological parameter, as it may influence the development and/or the course of acquired...

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Detalles Bibliográficos
Autores principales: Rondelli, Tommaso, Berardi, Margherita, Peruzzi, Benedetta, Boni, Luca, Caporale, Roberto, Dolara, Piero, Notaro, Rosario, Luzzatto, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544671/
https://www.ncbi.nlm.nih.gov/pubmed/23342069
http://dx.doi.org/10.1371/journal.pone.0054046