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A Reduction in Age-Enhanced Gluconeogenesis Extends Lifespan

The regulation of energy metabolism, such as calorie restriction (CR), is a major determinant of cellular longevity. Although augmented gluconeogenesis is known to occur in aged yeast cells, the role of enhanced gluconeogenesis in aged cells remains undefined. Here, we show that age-enhanced glucone...

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Detalles Bibliográficos
Autores principales: Hachinohe, Mayumi, Yamane, Midori, Akazawa, Daiki, Ohsawa, Kazuhiro, Ohno, Mayumi, Terashita, Yuzu, Masumoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544673/
https://www.ncbi.nlm.nih.gov/pubmed/23342062
http://dx.doi.org/10.1371/journal.pone.0054011