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PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

BACKGROUND: PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer (PCa) cells, but its functional role is unknown. To investigate its putative function in PCa biology, we used gene expression knockdown by small interference RNA, and also analyzed its involvement in androgen re...

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Detalles Bibliográficos
Autores principales: Ferreira, Luciana Bueno, Palumbo, Antonio, de Mello, Kivvi Duarte, Sternberg, Cinthya, Caetano, Mauricio S, de Oliveira, Felipe Leite, Neves, Adriana Freitas, Nasciutti, Luiz Eurico, Goulart, Luiz Ricardo, Gimba, Etel Rodrigues Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544699/
https://www.ncbi.nlm.nih.gov/pubmed/23130941
http://dx.doi.org/10.1186/1471-2407-12-507