Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

Thioredoxin system plays an important role in regulation of intracellular redox balance and various signaling pathways. Thioredoxin reductase (TrxR) is overexpressed in many cancer cells and has been identified as a potential target of anticancer drugs. Auranofin (AF) is potent TrxR inhibitor with n...

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Detalles Bibliográficos
Autores principales: Liu, Chaoran, Liu, Zhong, Li, Meng, Li, Xiaoling, Wong, Yum-Shing, Ngai, Sai-Ming, Zheng, Wenjie, Zhang, Yibo, Chen, Tianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544722/
https://www.ncbi.nlm.nih.gov/pubmed/23342042
http://dx.doi.org/10.1371/journal.pone.0053945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544722/
https://www.ncbi.nlm.nih.gov/pubmed/23342042
http://dx.doi.org/10.1371/journal.pone.0053945

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