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Akt1 Mediates Neuronal Differentiation in Zebrafish via a Reciprocal Interaction with Notch Signaling

Akt1 is well known for its role in regulating cell proliferation, differentiation, and apoptosis and is implicated in tumors and several neurological disorders. However, the role of Akt1 in neural development has not been well defined. We have isolated zebrafish akt1 and shown that this gene is prim...

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Detalles Bibliográficos
Autores principales: Cheng, Yi-Chuan, Hsieh, Fu-Yu, Chiang, Ming-Chang, Scotting, Paul J., Shih, Hung-Yu, Lin, Sheng-Jia, Wu, Hui-Lan, Lee, Han-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544797/
https://www.ncbi.nlm.nih.gov/pubmed/23342113
http://dx.doi.org/10.1371/journal.pone.0054262