Gene Expression Deregulation in Postnatal Skeletal Muscle of TK2 Deficient Mice Reveals a Lower Pool of Proliferating Myogenic Progenitor Cells

Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) depletion syndrome (MDS) in humans that predominantly affects skeletal muscle tissue. In mice, TK2 deficiency also affects several tissues in addition to skeletal muscle, including brain, heart, adipo...

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Detalles Bibliográficos
Autores principales: Paredes, João A., Zhou, Xiaoshan, Höglund, Stefan, Karlsson, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544874/
https://www.ncbi.nlm.nih.gov/pubmed/23341978
http://dx.doi.org/10.1371/journal.pone.0053698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544874/
https://www.ncbi.nlm.nih.gov/pubmed/23341978
http://dx.doi.org/10.1371/journal.pone.0053698

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