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Efficient Arsenic Metabolism — The AS3MT Haplotype Is Associated with DNA Methylation and Expression of Multiple Genes Around AS3MT

Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxicity is the efficiency of arsenic metabolism. The efficiency, in turn, is associated with non-coding single nucleotide polymorphisms (SNPs) in the arsenic methyltransferase AS3MT on chromosome 10q24. However,...

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Detalles Bibliográficos
Autores principales: Engström, Karin S., Hossain, Mohammad Bakhtiar, Lauss, Martin, Ahmed, Sultan, Raqib, Rubhana, Vahter, Marie, Broberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544896/
https://www.ncbi.nlm.nih.gov/pubmed/23341986
http://dx.doi.org/10.1371/journal.pone.0053732