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Immunologic Targeting of FOXP3 in Inflammatory Breast Cancer Cells

The forkhead transcription factor FOXP3 is necessary for induction of regulatory T lymphocytes (Tregs) and their immunosuppressive function. We have previously demonstrated that targeting Tregs by vaccination of mice with murine FOXP3 mRNA-transfected dendritic cells (DCs) elicits FOXP3-specific T c...

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Detalles Bibliográficos
Autores principales: Nair, Smita, Aldrich, Amy J., McDonnell, Eoin, Cheng, Qing, Aggarwal, Anshu, Patel, Pujan, Williams, Monique M., Boczkowski, David, Lyerly, H. Kim, Morse, Michael A., Devi, Gayathri R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544902/
https://www.ncbi.nlm.nih.gov/pubmed/23341929
http://dx.doi.org/10.1371/journal.pone.0053150