Cargando…

Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice

Metformin is used as an anti-diabetic drug. Metformin ameliorates insulin resistance by improving insulin sensitivity in liver and skeletal muscle. Reduced mitochondrial content has been reported in type 2 diabetic muscles and it may contribute to decreased insulin sensitivity characteristic for dia...

Descripción completa

Detalles Bibliográficos
Autores principales: Kristensen, Jonas M., Larsen, Steen, Helge, Jørn W., Dela, Flemming, Wojtaszewski, Jørgen F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544921/
https://www.ncbi.nlm.nih.gov/pubmed/23341947
http://dx.doi.org/10.1371/journal.pone.0053533