Cargando…

Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice

Metformin is used as an anti-diabetic drug. Metformin ameliorates insulin resistance by improving insulin sensitivity in liver and skeletal muscle. Reduced mitochondrial content has been reported in type 2 diabetic muscles and it may contribute to decreased insulin sensitivity characteristic for dia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kristensen, Jonas M., Larsen, Steen, Helge, Jørn W., Dela, Flemming, Wojtaszewski, Jørgen F. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544921/ https://www.ncbi.nlm.nih.gov/pubmed/23341947 http://dx.doi.org/10.1371/journal.pone.0053533

Ejemplares similares

High‐intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle
por: Dohlmann, Tine L., et al.
Publicado: (2018)

Reliability and variation in mitochondrial respiration in human adipose tissue
por: Sahl, Ronni Eg, et al.
Publicado: (2021)

Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study
por: Larsen, Steen, et al.
Publicado: (2018)

AMPK in skeletal muscle function and metabolism
por: Kjøbsted, Rasmus, et al.
Publicado: (2018)

Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
por: Jørgensen, Nicolas O., et al.
Publicado: (2018)

Simvastatin improves mitochondrial respiration in peripheral blood cells
por: Durhuus, Jon Ambæk, et al.
Publicado: (2020)

Metformin does not compromise energy status in human skeletal muscle at rest or during acute exercise: A randomised, crossover trial
por: Kristensen, Jonas M., et al.
Publicado: (2019)

Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise
por: Hingst, Janne R., et al.
Publicado: (2020)

Peak Fat Oxidation Rate Is Closely Associated With Plasma Free Fatty Acid Concentrations in Women; Similar to Men
por: Frandsen, Jacob, et al.
Publicado: (2021)

5′-AMP Activated Protein Kinase is Involved in the Regulation of Myocardial β-Oxidative Capacity in Mice
por: Stride, Nis, et al.
Publicado: (2012)

AMPK α(1) Activation Is Required for Stimulation of Glucose Uptake by Twitch Contraction, but Not by H(2)O(2), in Mouse Skeletal Muscle
por: Jensen, Thomas E., et al.
Publicado: (2008)

AMPK and Insulin Action - Responses to Ageing and High Fat Diet
por: Frøsig, Christian, et al.
Publicado: (2013)

Peripheral blood mononuclear cells exhibit increased mitochondrial respiration after adjuvant chemo‐ and radiotherapy for early breast cancer
por: Christensen, Ida Bager, et al.
Publicado: (2023)

AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores
por: Kido, Kohei, et al.
Publicado: (2023)

COMPARATIVE STUDIES ON RESPIRATION : XXIV. THE EFFECTS OF CHLOROFORM ON THE RESPIRATION OF DEAD AND OF LIVING TISSUE.
por: Ray, George B.
Publicado: (1923)

Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles
por: CHRISTIANSEN, Liselotte Bruun, et al.
Publicado: (2015)

Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
por: Jørgensen, Nicolas O., et al.
Publicado: (2021)

Results from (11)C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly
por: Iversen, Ane B., et al.
Publicado: (2017)

ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα(2)
por: Fritzen, Andreas Mæchel, et al.
Publicado: (2020)

The Response of Mitochondrial Respiration and Quantity in Skeletal Muscle and Adipose Tissue to Exercise in Humans with Prediabetes
por: Szczerbinski, Lukasz, et al.
Publicado: (2021)

An Optimized Histochemical Method to Assess Skeletal Muscle Glycogen and Lipid Stores Reveals Two Metabolically Distinct Populations of Type I Muscle Fibers
por: Prats, Clara, et al.
Publicado: (2013)

AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles
por: Jensen, Jørgen, et al.
Publicado: (2017)

Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training
por: Søgaard, Ditte, et al.
Publicado: (2019)

Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
por: Pedersen, Julie S., et al.
Publicado: (2022)

Counting the dead: the epidemiology of skeletal populations
por: Manchester, Keith
Publicado: (1995)

Defining the Contribution of AMP-activated Protein Kinase (AMPK) and Protein Kinase C (PKC) in Regulation of Glucose Uptake by Metformin in Skeletal Muscle Cells
por: Turban, Sophie, et al.
Publicado: (2012)

Metabolic regulation by the intestinal metformin-AMPK axis
por: Zhang, Song-Yang, et al.
Publicado: (2022)

Coenzyme Q10 Supplementation in Statin Treated Patients: A Double-Blinded Randomized Placebo-Controlled Trial
por: Dohlmann, Tine L., et al.
Publicado: (2022)

Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time- and intensity-dependent manner
por: Baranowski, Marcin, et al.
Publicado: (2014)

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms
por: Chen, Suet Ching, et al.
Publicado: (2017)

Metabolic effects of alternate-day fasting in males with obesity with or without type 2 diabetes
por: Ingersen, Arthur, et al.
Publicado: (2022)

Aerobic and resistance exercise training reverses age‐dependent decline in NAD(+) salvage capacity in human skeletal muscle
por: de Guia, Roldan M., et al.
Publicado: (2019)

The effectiveness of body age-based intervention in workplace health promotion: Results of a cohort study on 9851 Danish employees
por: Husted, Karina L. S., et al.
Publicado: (2020)

The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective
por: Agius, Loranne, et al.
Publicado: (2020)

Demystifying the Relationship Between Metformin, AMPK, and Doxorubicin Cardiotoxicity
por: Singh, Manrose, et al.
Publicado: (2022)

Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption
por: Lewis, Christopher T.A., et al.
Publicado: (2023)

Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism
por: Barlow, Jonathan P., et al.
Publicado: (2020)

Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes
por: Sabaratnam, Rugivan, et al.
Publicado: (2018)

Molecular Mechanism by Which AMP-Activated Protein Kinase Activation Promotes Glycogen Accumulation in Muscle
por: Hunter, Roger W., et al.
Publicado: (2011)

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation
por: Groenendijk, Floris H, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_eds2qtoou19m89vsq79hfilvdu