Novel Selective and Irreversible Mosquito Acetylcholinesterase Inhibitors for Controlling Malaria and Other Mosquito-Borne Diseases

We reported previously that insect acetylcholinesterases (AChEs) could be selectively and irreversibly inhibited by methanethiosulfonates presumably through conjugation to an insect-specific cysteine in these enzymes. However, no direct proof for the conjugation has been published to date, and doubt...

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Detalles Bibliográficos
Autores principales: Dou, Dengfeng, Park, Jewn Giew, Rana, Sandeep, Madden, Benjamin J., Jiang, Haobo, Pang, Yuan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545233/
https://www.ncbi.nlm.nih.gov/pubmed/23323211
http://dx.doi.org/10.1038/srep01068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545233/
https://www.ncbi.nlm.nih.gov/pubmed/23323211
http://dx.doi.org/10.1038/srep01068

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