MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila

The abundance of Myc protein must be exquisitely controlled to avoid growth abnormalities caused by too much or too little Myc. An intriguing mode of regulation exists in which Myc protein itself leads to reduction in its abundance. We show here that dMyc binds to the miR-308 locus and increases its...

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Detalles Bibliográficos
Autores principales: Daneshvar, Kaveh, Nath, Sritama, Khan, Abid, Shover, Wesley, Richardson, Christine, Goodliffe, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545263/
https://www.ncbi.nlm.nih.gov/pubmed/23336071
http://dx.doi.org/10.1242/bio.20122725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545263/
https://www.ncbi.nlm.nih.gov/pubmed/23336071
http://dx.doi.org/10.1242/bio.20122725

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