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Suppressor mutations identify amino acids in PAA-1/PR65 that facilitate regulatory RSA-1/B″ subunit targeting of PP2A to centrosomes in C. elegans

Protein phosphorylation and dephosphorylation is a key mechanism for the spatial and temporal regulation of many essential developmental processes and is especially prominent during mitosis. The multi-subunit protein phosphatase 2A (PP2A) enzyme plays an important, yet poorly characterized role in d...

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Detalles Bibliográficos
Autores principales: Lange, Karen I., Heinrichs, Jeffrey, Cheung, Karen, Srayko, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545272/
https://www.ncbi.nlm.nih.gov/pubmed/23336080
http://dx.doi.org/10.1242/bio.20122956