Dissecting the mechanisms of Notch induced hyperplasia

The outcome of the Notch pathway on proliferation depends on cellular context, being growth promotion in some, including several cancers, and growth inhibition in others. Such disparate outcomes are evident in Drosophila wing discs, where Notch overactivation causes hyperplasia despite having locali...

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Detalles Bibliográficos
Autores principales: Djiane, Alexandre, Krejci, Alena, Bernard, Frédéric, Fexova, Silvie, Millen, Katherine, Bray, Sarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545308/
https://www.ncbi.nlm.nih.gov/pubmed/23232763
http://dx.doi.org/10.1038/emboj.2012.326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545308/
https://www.ncbi.nlm.nih.gov/pubmed/23232763
http://dx.doi.org/10.1038/emboj.2012.326

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