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A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease

BACKGROUND: Glioblastomas are the most common central nervous system neoplasia in adults, with 9,000 cases in the US annually. Glioblastoma multiformae, the most aggressive glioma subtype, has an 18% one-year survival rate, and 3% two year survival rate. Recent work has highlighted the role of the t...

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Detalles Bibliográficos
Autores principales: Wagoner, Matthew P, Roopra, Avtar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545737/
https://www.ncbi.nlm.nih.gov/pubmed/23216891
http://dx.doi.org/10.1186/1471-2164-13-686