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A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease
BACKGROUND: Glioblastomas are the most common central nervous system neoplasia in adults, with 9,000 cases in the US annually. Glioblastoma multiformae, the most aggressive glioma subtype, has an 18% one-year survival rate, and 3% two year survival rate. Recent work has highlighted the role of the t...
Autores principales: | Wagoner, Matthew P, Roopra, Avtar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545737/ https://www.ncbi.nlm.nih.gov/pubmed/23216891 http://dx.doi.org/10.1186/1471-2164-13-686 |
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