Two large-scale analyses of Ty1 LTR-retrotransposon de novo insertion events indicate that Ty1 targets nucleosomal DNA near the H2A/H2B interface

BACKGROUND: Over the years, a number of reports have revealed that Ty1 integration occurs in a 1-kb window upstream of Pol III-transcribed genes with an approximate 80-bp periodicity between each integration hotspot and that this targeting requires active Pol III transcription at the site of integra...

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Detalles Bibliográficos
Autores principales: Bridier-Nahmias, Antoine, Lesage, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545840/
https://www.ncbi.nlm.nih.gov/pubmed/23244340
http://dx.doi.org/10.1186/1759-8753-3-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545840/
https://www.ncbi.nlm.nih.gov/pubmed/23244340
http://dx.doi.org/10.1186/1759-8753-3-22

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