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Tim-3 Expression in Cervical Cancer Promotes Tumor Metastasis

BACKGROUND: T cell immunoglobulin mucin-3 (Tim-3) has been identified as a negative regulator of anti-tumor immunity. Recent studies highlight the important role of Tim-3 in the CD8(+) T cell exhaustion that takes place in both human and animal cancer models. However, the nature of Tim-3 expression...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Zhou, Xiaoxi, Huang, Xiaoyuan, Li, Qinlu, Gao, Lili, Jiang, Lijun, Huang, Mei, Zhou, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545875/
https://www.ncbi.nlm.nih.gov/pubmed/23335978
http://dx.doi.org/10.1371/journal.pone.0053834