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Transcriptional Effects of E3 Ligase Atrogin-1/MAFbx on Apoptosis, Hypertrophy and Inflammation in Neonatal Rat Cardiomyocytes

Atrogin-1/MAFbx is an ubiquitin E3 ligase that regulates myocardial structure and function through the ubiquitin-dependent protein modification. However, little is known about the effect of atrogin-1 activation on the gene expression changes in cardiomyocytes. Neonatal rat cardiomyocytes were infect...

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Detalles Bibliográficos
Autores principales: Zeng, Yong, Wang, Hong-Xia, Guo, Shu-Bin, Yang, Hui, Zeng, Xiang-Jun, Fang, Quan, Tang, Chao-Shu, Du, Jie, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545877/
https://www.ncbi.nlm.nih.gov/pubmed/23335977
http://dx.doi.org/10.1371/journal.pone.0053831