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Transcriptional Effects of E3 Ligase Atrogin-1/MAFbx on Apoptosis, Hypertrophy and Inflammation in Neonatal Rat Cardiomyocytes
Atrogin-1/MAFbx is an ubiquitin E3 ligase that regulates myocardial structure and function through the ubiquitin-dependent protein modification. However, little is known about the effect of atrogin-1 activation on the gene expression changes in cardiomyocytes. Neonatal rat cardiomyocytes were infect...
Autores principales: | Zeng, Yong, Wang, Hong-Xia, Guo, Shu-Bin, Yang, Hui, Zeng, Xiang-Jun, Fang, Quan, Tang, Chao-Shu, Du, Jie, Li, Hui-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545877/ https://www.ncbi.nlm.nih.gov/pubmed/23335977 http://dx.doi.org/10.1371/journal.pone.0053831 |
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