Aminoglycosylation Can Enhance the G-Quadruplex Binding Activity of Epigallocatechin

With the aim of enhancing G-quadruplex binding activity, two new glucosaminosides (16, 18) of penta-methylated epigallocatechin were synthesized by chemical glycosylation. Subsequent ESI-TOF-MS analysis demonstrated that these two glucosaminoside derivatives exhibit much stronger binding activity to...

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Detalles Bibliográficos
Autores principales: Bai, Li-Ping, Ho, Hing-Man, Ma, Dik-Lung, Yang, Hui, Fu, Wai-Chung, Jiang, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545880/
https://www.ncbi.nlm.nih.gov/pubmed/23335983
http://dx.doi.org/10.1371/journal.pone.0053962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545880/
https://www.ncbi.nlm.nih.gov/pubmed/23335983
http://dx.doi.org/10.1371/journal.pone.0053962

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