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Aminoglycosylation Can Enhance the G-Quadruplex Binding Activity of Epigallocatechin
With the aim of enhancing G-quadruplex binding activity, two new glucosaminosides (16, 18) of penta-methylated epigallocatechin were synthesized by chemical glycosylation. Subsequent ESI-TOF-MS analysis demonstrated that these two glucosaminoside derivatives exhibit much stronger binding activity to...
Autores principales: | Bai, Li-Ping, Ho, Hing-Man, Ma, Dik-Lung, Yang, Hui, Fu, Wai-Chung, Jiang, Zhi-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545880/ https://www.ncbi.nlm.nih.gov/pubmed/23335983 http://dx.doi.org/10.1371/journal.pone.0053962 |
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