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Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation

BACKGROUND: Irritable bowel syndrome (IBS) is characterized by chronic visceral hyperalgesia (CVH) that manifested with persistent or recurrent abdominal pain and altered bowel movement. However, the pathogenesis of the CVH remains unknown. The aim of this study was to investigate roles of endogenou...

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Detalles Bibliográficos
Autores principales: Li, Lin, Xie, Ruihua, Hu, Shufen, Wang, Yongmeng, Yu, Tianzhu, Xiao, Ying, Jiang, Xinghong, Gu, Jianguo, Hu, Chuang-Ying, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545973/
https://www.ncbi.nlm.nih.gov/pubmed/23249427
http://dx.doi.org/10.1186/1744-8069-8-89