The structure of Human Microplasmin in Complex with Textilinin-1, an Aprotinin-like Inhibitor from the Australian Brown Snake

Textilinin-1 is a Kunitz-type serine protease inhibitor from Australian brown snake venom. Its ability to potently and specifically inhibit human plasmin (K(i) = 0.44 nM) makes it a potential therapeutic drug as a systemic anti-bleeding agent. The crystal structures of the human microplasmin-textili...

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Detalles Bibliográficos
Autores principales: Millers, Emma-Karin I., Johnson, Lambro A., Birrell, Geoff W., Masci, Paul P., Lavin, Martin F., de Jersey, John, Guddat, Luke W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545990/
https://www.ncbi.nlm.nih.gov/pubmed/23335990
http://dx.doi.org/10.1371/journal.pone.0054104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545990/
https://www.ncbi.nlm.nih.gov/pubmed/23335990
http://dx.doi.org/10.1371/journal.pone.0054104

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