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An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

BACKGROUND: Following exposure via inhalation, intratracheal instillation or ingestion some nanomaterials (NM) have been shown to translocate to the liver. Since oxidative stress has been implicated as a possible mechanism for NM toxicity this study aimed to investigate the effects of various materi...

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Detalles Bibliográficos
Autores principales: Kermanizadeh, Ali, Gaiser, Birgit K, Hutchison, Gary R, Stone, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546021/
https://www.ncbi.nlm.nih.gov/pubmed/22812506
http://dx.doi.org/10.1186/1743-8977-9-28