Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth

BACKGROUND: Constitutive activation of Ras in immortalized bronchial epithelial cells increases electron transport chain activity, oxygen consumption and tricarboxylic acid cycling through unknown mechanisms. We hypothesized that members of the Ras family may stimulate respiration by enhancing the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Telang, Sucheta, Nelson, Kristin K, Siow, Deanna L, Yalcin, Abdullah, Thornburg, Joshua M, Imbert-Fernandez, Yoannis, Klarer, Alden C, Farghaly, Hanan, Clem, Brian F, Eaton, John W, Chesney, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546037/
https://www.ncbi.nlm.nih.gov/pubmed/22917272
http://dx.doi.org/10.1186/1476-4598-11-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546037/
https://www.ncbi.nlm.nih.gov/pubmed/22917272
http://dx.doi.org/10.1186/1476-4598-11-60

Ejemplares similares