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Genetic Variation in Plant CYP51s Confers Resistance against Voriconazole, a Novel Inhibitor of Brassinosteroid-Dependent Sterol Biosynthesis

Brassinosteroids (BRs) are plant steroid hormones with structural similarity to mammalian sex steroids and ecdysteroids from insects. The BRs are synthesized from sterols and are essential regulators of cell division, cell elongation and cell differentiation. In this work we show that voriconazole,...

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Detalles Bibliográficos
Autores principales: Rozhon, Wilfried, Husar, Sigrid, Kalaivanan, Florian, Khan, Mamoona, Idlhammer, Markus, Shumilina, Daria, Lange, Theo, Hoffmann, Thomas, Schwab, Wilfried, Fujioka, Shozo, Poppenberger, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546049/
https://www.ncbi.nlm.nih.gov/pubmed/23335967
http://dx.doi.org/10.1371/journal.pone.0053650