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Involvement of IL-9 in Th17-Associated Inflammation and Angiogenesis of Psoriasis

It is thought that a Th1/Th17-weighted immune response plays a predominant role in the pathogenesis of psoriasis. Our findings now indicate a link between IL-9, a Th2 and Th9 cytokine, and Th17 pathway in psoriasis. In K5.hTGF-β1 transgenic mice, exhibiting a psoriasis-like phenotype, we found incre...

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Detalles Bibliográficos
Autores principales: Singh, Tej Pratap, Schön, Michael P., Wallbrecht, Katrin, Gruber-Wackernagel, Alexandra, Wang, Xiao-Jing, Wolf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546056/
https://www.ncbi.nlm.nih.gov/pubmed/23335955
http://dx.doi.org/10.1371/journal.pone.0051752