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The Blocking of c-Met Signaling Induces Apoptosis through the Increase of p53 Protein in Lung Cancer

PURPOSE: c-Met is an attractive potential target for novel therapeutic inhibition of human cancer, and c-Met tyrosine kinase inhibitors (TKIs) are effective growth inhibitors of various malignancies. However, their mechanisms in anticancer effects are not clear. In the present study, we investigated...

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Detalles Bibliográficos
Autores principales: Jung, Hae-Yun, Joo, Hyun-Jung, Park, Jong Kuk, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546272/
https://www.ncbi.nlm.nih.gov/pubmed/23341789
http://dx.doi.org/10.4143/crt.2012.44.4.251