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Order within disorder: Aggrecan chondroitin sulphate-attachment region provides new structural insights into protein sequences classified as disordered

Structural investigation of proteins containing large stretches of sequences without predicted secondary structure is the focus of much increased attention. Here, we have produced an unglycosylated 30 kDa peptide from the chondroitin sulphate (CS)-attachment region of human aggrecan (CS-peptide), wh...

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Detalles Bibliográficos
Autores principales: Jowitt, Thomas A, Murdoch, Alan D, Baldock, Clair, Berry, Richard, Day, Joanna M, Hardingham, Timothy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546398/
https://www.ncbi.nlm.nih.gov/pubmed/20806220
http://dx.doi.org/10.1002/prot.22839