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Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives

The development of an animal model of human immunodeficiency virus type 1 (HIV-1)/AIDS that is suitable for preclinical testing of antiretroviral therapy, vaccines, curative strategies, and studies of pathogenesis has been hampered by the human-specific tropism of HIV-1. Although simian immunodefici...

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Detalles Bibliográficos
Autores principales: Thippeshappa, Rajesh, Ruan, Hongmei, Kimata, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546514/
https://www.ncbi.nlm.nih.gov/pubmed/23336082
http://dx.doi.org/10.3390/biology1020134