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Ginsenoside Rh2 Induces Human Hepatoma Cell Apoptosis via Bax/Bak Triggered Cytochrome C Release and Caspase-9/Caspase-8 Activation

Ginsenoside Rh2 (G-Rh2) has been shown to induce apoptotic cell death in a variety of cancer cells. However, the details of the signal transduction cascade involved in G-Rh2-induced cell death is unclear. In this manuscript we elucidate the molecular mechanism of G-Rh2-induced apoptosis in human hep...

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Detalles Bibliográficos
Autores principales: Guo, Xiao-Xi, Guo, Qiao, Li, Yang, Lee, Seung Ki, Wei, Xue-Ning, Jin, Ying-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546647/
https://www.ncbi.nlm.nih.gov/pubmed/23443079
http://dx.doi.org/10.3390/ijms131215523