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Base Excision Repair in Physiology and Pathology of the Central Nervous System

Relatively low levels of antioxidant enzymes and high oxygen metabolism result in formation of numerous oxidized DNA lesions in the tissues of the central nervous system. Accumulation of damage in the DNA, due to continuous genotoxic stress, has been linked to both aging and the development of vario...

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Detalles Bibliográficos
Autores principales: Bosshard, Matthias, Markkanen, Enni, van Loon, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546685/
https://www.ncbi.nlm.nih.gov/pubmed/23203191
http://dx.doi.org/10.3390/ijms131216172