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Base Excision Repair in Physiology and Pathology of the Central Nervous System
Relatively low levels of antioxidant enzymes and high oxygen metabolism result in formation of numerous oxidized DNA lesions in the tissues of the central nervous system. Accumulation of damage in the DNA, due to continuous genotoxic stress, has been linked to both aging and the development of vario...
Autores principales: | Bosshard, Matthias, Markkanen, Enni, van Loon, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546685/ https://www.ncbi.nlm.nih.gov/pubmed/23203191 http://dx.doi.org/10.3390/ijms131216172 |
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