1-Benzyl-2-Phenylbenzimidazole (BPB), a Benzimidazole Derivative, Induces Cell Apoptosis in Human Chondrosarcoma through Intrinsic and Extrinsic Pathways

In this study, we investigated the anticancer effects of a new benzimidazole derivative, 1-benzyl-2-phenyl -benzimidazole (BPB), in human chondrosarcoma cells. BPB-mediated apoptosis was assessed by the MTT assay and flow cytometry analysis. The in vivo efficacy was examined in a JJ012 xenograft mod...

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Detalles Bibliográficos
Autores principales: Liu, Ju-Fang, Huang, Yuan-Li, Yang, Wei-Hung, Chang, Chih-Shiang, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546702/
https://www.ncbi.nlm.nih.gov/pubmed/23211670
http://dx.doi.org/10.3390/ijms131216472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546702/
https://www.ncbi.nlm.nih.gov/pubmed/23211670
http://dx.doi.org/10.3390/ijms131216472

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