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Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure

Carboplatin-paclitaxel is a reference regimen in the treatment of locally advanced or disseminated non-small cell lung cancer (NSCLC). This paper discusses the multidrug resistance developed with this drug combination, which is one of the major obstacles to successful treatment. In order to understa...

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Detalles Bibliográficos
Autores principales: Melguizo, Consolación, Prados, Jose, Luque, Raquel, Ortiz, Raúl, Caba, Octavio, Álvarez, Pablo J., Gonzalez, Beatriz, Aranega, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546711/
https://www.ncbi.nlm.nih.gov/pubmed/23443122
http://dx.doi.org/10.3390/ijms131216624