A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

Motivation: The Illumina Infinium 450 k DNA Methylation Beadchip is a prime candidate technology for Epigenome-Wide Association Studies (EWAS). However, a difficulty associated with these beadarrays is that probes come in two different designs, characterized by widely different DNA methylation distr...

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Detalles Bibliográficos
Autores principales: Teschendorff, Andrew E., Marabita, Francesco, Lechner, Matthias, Bartlett, Thomas, Tegner, Jesper, Gomez-Cabrero, David, Beck, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546795/
https://www.ncbi.nlm.nih.gov/pubmed/23175756
http://dx.doi.org/10.1093/bioinformatics/bts680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546795/
https://www.ncbi.nlm.nih.gov/pubmed/23175756
http://dx.doi.org/10.1093/bioinformatics/bts680

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