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High-throughput microbial population genomics using the Cortex variation assembler

Summary: We have developed a software package, Cortex, designed for the analysis of genetic variation by de novo assembly of multiple samples. This allows direct comparison of samples without using a reference genome as intermediate and incorporates discovery and genotyping of single-nucleotide poly...

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Detalles Bibliográficos
Autores principales: Iqbal, Zamin, Turner, Isaac, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546798/
https://www.ncbi.nlm.nih.gov/pubmed/23172865
http://dx.doi.org/10.1093/bioinformatics/bts673