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Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity ba...

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Detalles Bibliográficos
Autores principales: White, Nicholas J, Qiao, Li Guo, Qi, Gao, Luzzatto, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546849/
https://www.ncbi.nlm.nih.gov/pubmed/23237606
http://dx.doi.org/10.1186/1475-2875-11-418