Cargando…

Over-expression of mitochondrial antiviral signaling protein inhibits coxsackievirus B3 infection by enhancing type-I interferons production

BACKGROUND: Recent studies have revealed that Mitochondrial Antiviral Signaling (MAVS) protein plays an essential role in the inhibition of viral infection through type I interferon (IFN) pathway. It has been shown that 3C (pro) cysteine protease of coxsackievirus B3 (CVB3) cleaves MAVS to inhibit t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qing-Meng, Song, Wu-Qi, Li, Yu-Jun, Qian, Jun, Zhai, Ai-Xia, Wu, Jing, Li, Ai-Mei, He, Jun-Ming, Zhao, Jin-Yun, Yu, Xin, Wei, Lan-Lan, Zhang, Feng-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546859/
https://www.ncbi.nlm.nih.gov/pubmed/23249700
http://dx.doi.org/10.1186/1743-422X-9-312