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Over-expression of mitochondrial antiviral signaling protein inhibits coxsackievirus B3 infection by enhancing type-I interferons production
BACKGROUND: Recent studies have revealed that Mitochondrial Antiviral Signaling (MAVS) protein plays an essential role in the inhibition of viral infection through type I interferon (IFN) pathway. It has been shown that 3C (pro) cysteine protease of coxsackievirus B3 (CVB3) cleaves MAVS to inhibit t...
Autores principales: | Zhang, Qing-Meng, Song, Wu-Qi, Li, Yu-Jun, Qian, Jun, Zhai, Ai-Xia, Wu, Jing, Li, Ai-Mei, He, Jun-Ming, Zhao, Jin-Yun, Yu, Xin, Wei, Lan-Lan, Zhang, Feng-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546859/ https://www.ncbi.nlm.nih.gov/pubmed/23249700 http://dx.doi.org/10.1186/1743-422X-9-312 |
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