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Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

BACKGROUND: Recent fate-mapping studies establish that microglia, the resident mononuclear phagocytes of the CNS, are distinct in origin from the bone marrow-derived myeloid lineage. Interferon regulatory factor 8 (IRF8, also known as interferon consensus sequence binding protein) plays essential ro...

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Detalles Bibliográficos
Autores principales: Horiuchi, Makoto, Wakayama, Kouji, Itoh, Aki, Kawai, Kumi, Pleasure, David, Ozato, Keiko, Itoh, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546867/
https://www.ncbi.nlm.nih.gov/pubmed/23020843
http://dx.doi.org/10.1186/1742-2094-9-227