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Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

BACKGROUND: Recent fate-mapping studies establish that microglia, the resident mononuclear phagocytes of the CNS, are distinct in origin from the bone marrow-derived myeloid lineage. Interferon regulatory factor 8 (IRF8, also known as interferon consensus sequence binding protein) plays essential ro...

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Detalles Bibliográficos
Autores principales:	Horiuchi, Makoto, Wakayama, Kouji, Itoh, Aki, Kawai, Kumi, Pleasure, David, Ozato, Keiko, Itoh, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546867/ https://www.ncbi.nlm.nih.gov/pubmed/23020843 http://dx.doi.org/10.1186/1742-2094-9-227

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