Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration

BACKGROUND: The recruitment and activation of inflammatory cells is thought to exacerbate photoreceptor death in retinal degenerative conditions such as age-related macular degeneration (AMD). We investigated the role of Müller cell-derived chemokine (C-C motif) ligand (Ccl)2 expression on monocyte/...

Descripción completa

Detalles Bibliográficos
Autores principales: Rutar, Matt, Natoli, Riccardo, Provis, Jan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546872/
https://www.ncbi.nlm.nih.gov/pubmed/22992301
http://dx.doi.org/10.1186/1742-2094-9-221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546872/
https://www.ncbi.nlm.nih.gov/pubmed/22992301
http://dx.doi.org/10.1186/1742-2094-9-221

Ejemplares similares