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Development and validation of a Q-PCR based TCID(50) method for human herpesvirus 6

BACKGROUND: For titer assessment of human herpesvirus 6 (HHV-6), IFA targeting viral proteins or a TCID(50) method with ocular inspection for CPE can be used. These methods rely on the subjective decision of the assessor, obstructing the ability to obtain unanimous results. FINDINGS: We have develop...

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Detalles Bibliográficos
Autores principales: Gustafsson, Rasmus K L, Engdahl, Elin E, Fogdell-Hahn, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546908/
https://www.ncbi.nlm.nih.gov/pubmed/23249654
http://dx.doi.org/10.1186/1743-422X-9-311