GLP-1 secretion by microglial cells and decreased CNS expression in obesity

BACKGROUND: Type 2 diabetes (T2D) is a strong risk factor for developing neurodegenerative pathologies. T2D patients have a deficiency in the intestinal incretin hormone GLP-1, which has been shown to exert neuroprotective and anti-inflammatory properties in the brain. METHODS: Here we investigate p...

Descripción completa

Detalles Bibliográficos
Autores principales: Kappe, Camilla, Tracy, Linda M, Patrone, Cesare, Iverfeldt, Kerstin, Sjöholm, Åke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546916/
https://www.ncbi.nlm.nih.gov/pubmed/23259618
http://dx.doi.org/10.1186/1742-2094-9-276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546916/
https://www.ncbi.nlm.nih.gov/pubmed/23259618
http://dx.doi.org/10.1186/1742-2094-9-276

Ejemplares similares